2021 USCAP Maude Abbott Lecture - Neuroendocrine Carcinomas yeMusoro neMutsipa:
Ramangwana, Ranhasi uye Rinogoneka

BRUCE M. WENIG, MD

Sachigaro uye Mutezo Mukuru
Dhipatimendi rePathology
Moffitt Cancer Center
Purofesa weOncological Sayenzi
University of South Florida
Tamba, FL

Nguva yekumhanya: 1 awa 26 Maminitsi

PROGRAM ZVIRI MUKATI

Neuroendocrine neoplasms (NEN) inomuka munharaunda yese. Kukura kwe embryologic kweNEN kwave kuri nyaya yekukakavadzana kana paine kana kuti kwete yakajairika neural crest yakabva. Pasi pechisikwa chezvakajairwa neural crest kwakabva, kuvepo kweyakajairika biochemical nzira mumaseru euroendocrine anosanganisira kutora uye decarboxylation yeamine precursors yakamisikidzwa ichibvumira kuti masero aya aonekwe histochemically uye zvichikonzera kushandiswa kweacronym APUD (Amine Precursor. Uptake uye Decarboxylation) kutsanangura maseru ari mune ino system. Zvidzidzo zvakazotevera zvakaburitsa zvakajairika neural crest mavambo uye kupatsanurwa kweDispered Neuroendocrine Cell System yakagamuchirwa kuNEN. Kurongeka kweNEN kwave neshanduko apo zvirongwa zvazvino zvisinei nenzvimbo yekwakabva zvakakurudzira kushandisa nomenclature yakatemerwa gastrointestinal uye pancreatic NEN. Kunze kwegastrointestinal turakiti, pancreas nemapapu, nzvimbo yemusoro nemutsipa iri pakati penzvimbo dzinowanzoitika kuitika kweNEN uye mukati meiyi nharaunda neuroendocrine carcinoma ndiyo yakajairika mhando yesaiti chaiyo NEN. Hurukuro iyi ichatarisa neuroendocrine carcinomas yemusoro nemutsipa ichiongorora maitiro avo ekiriniki uye kukurukura kuisirwa kwavo mukati meiyo yunifomu yemhando yehurongwa yakarongwa kune imwe saiti chaiyo NEN.

KUDZIDZA ZVINANGWA

1. Kurukurai embryologic kukura kweneuroendocrine neoplasms
2. Rondedzera nzira yekuongorora yemusoro nemutsipa neuroendocrine neoplasms inosiyanisa aya maitiro kune ayo eimwe saiti chaiyo NEN.
3. Sarudza kana iyo yakatsanangurwa yakajairwa dhizaini yeNEN inoshanda kune musoro nemutsipa NEN